Dr. Ronnie H. Fang is currently an assistant project scientist in the Department of NanoEngineering at the University of California, San Diego (UCSD) doing research on biomimetic nanoparticle technologies. He obtained his B.S. degrees in Engineering Physics and Biochemistry & Cell Biology before earning his Ph.D. in NanoEngineering under the mentorship of Dr. Liangfang Zhang, all at UCSD. (more)

Research

Biomimetic nanoparticles seek to mimic many properties found in nature. My work involves the use of cell membrane-derived coatings to functionalize synthetic nanoparticles, creating a natural-synthetic hybrid structure that retains many of the properties of the original cells. This platform technology can be generalized to many different types of cell membrane types and different core materials. My goal is to apply these new class of particles to solve challenging issues facing modern medicine. Visit the Research page to learn more!

News

2019
  • June 7th - A research article on macrophage-based nanotoxoids for multiantigenic vaccination against Gram-negative bacteria was accepted for publication in Nano Letters.
  • April 15th - A review article on biomimetic nanotechnology towards personalized vaccines was accepted for publication in Advanced Materials.
  • January 18th - A research article on motor-driven nanotoxoids for mucosal vaccination was accepted for publication in Nano Letters.
2018
  • October 25th - A review article on biomimetic nanoparticle vaccines for cancer therapy was accepted for publication in Advanced Biosystems.
  • October 14th - A review article on engineering biological interactions at the nanoscale was accepted for publication in Current Opinion in Biotechnology.
  • September 10th - A research article on biomimetic nanoemulsions for oxygen delivery was accepted for publication in Advanced Materials.
  • August 2nd​ - A research article on neutrophil membrane-coated nanosponges for arthritis treatment was accepted for publication in Nature Nanotechnology.
  • ​May 11th - A review article on tissue repair and regeneration using endogenous stem cells was accepted for publication in Nature Reviews Materials.
  • March 20th - A research article on remote loading of small molecule drugs into platelet membrane vesicles was accepted for publication in Advanced Functional Materials.
  • March 13th - A research article on the biomimetic targeting of immune cells using cognate antigen interactions was accepted for publication in Molecular Pharmaceutics.
  • ​January 22nd - An invited review on biomimetic nanosponges for treating antibody-mediated autoimmune diseases was accepted for publication in Bioconjugate Chemistry.
2017
  • December 14th - An invited review on biomimetic nanotoxoids was accepted for publication in Bioconjugate Chemistry.
  • December 12th - An invited review on cell membrane-coated nanotechnology was accepted for publication in Advanced Materials.
  • December 8th - A research article on platelet membrane-coated nanoparticles for the biological detection of atherosclerosis was accepted for publication in ACS Nano.
  • September 13th - A research article on cancer cell membrane coated nanoparticles for anticancer vaccination was accepted for publication in Advanced Materials.
  • September 11th - A research article on applying membrane-coated nanoparticles for the identification of virulence factors was accepted for publication in ACS Nano.
  • September 11th - A research article on remote loading of small molecule drugs into cholesterol-enriched membrane vesicles was accepted for publication in Angewandte Chemie International Edition.
  • May 22nd - A research article on the in situ capture of bacterial proteins for antivirulence vaccination was accepted for publication in ​Advanced Materials.
  • April 24th - An invited review on the preparation of polymeric therapeutics was accepted for publication in Small Methods.
  • February 28th - An invited review on cell membrane-derived nanomaterials for biomedical applications was accepted for publication in ​Biomaterials.
  • January 17th - A research article on RBC-platelet hybrid membrane-coated nanoparticles was accepted for publication in ​Advanced Materials.​
2016
  • October 31st - An invited review on cell membrane-coated nanoparticles was accepted for publication in Bioconjugate Chemistry.
  • October 1st - A research article on platelet membrane-coated nanoparticle for immune thrombocytopenia treatment was accepted for publication in Biomaterials.
  • July 5th - A research article on ultra-small hybrid nanoparticle for tumor-penetrating drug delivery was accepted for publication in Nanoscale.
  • April 21st - An invited review on nanoparticle-based modulation of the immune system was published in Annual Review of Chemical and Biomolecular Engineering.
  • April 8th - An invited review on biomimetic targeting strategies was accepted for publication in Bioengineering & Translational Medicine.
  • January 4th - A research article on a nanoparticle-based anti-virulence vaccine against MRSA was accepted for publication in Advanced Functional Materials.​
2015
  • December 11th - A research article on RBC membrane-coated nanoparticles for treatment of solid tumors was accepted for publication in Theranostics.
  • August 12th - A research article on using platelet membrane coatings for nanoparticle biointerfacing was accepted for publication in Nature​.
  • June 22nd - An invited review on nanoparticle-based manipulation of antigen presenting cells for cancer immunotherapy was accepted for publication in Small.
  • May 30th - A research article on using RBC membrane-coated nanoparticles to treat organophosphate poisoning was accepted for publication in ACS Nano.
  • May 15th - A research article on cell membrane-templated synthesis of nanogels was accepted for publication in Small.
  • April 1st - An invited review on nanoparticle-based toxin neutralization was accepted for publication in Advanced Drug Delivery Reviews.​